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Browse Mutations mdtBG610C

GenemdtB

efflux pump component

Nucleotide ChangeG610C

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduces cloxacillin efflux activity
Resistance To: cloxacillin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Different functions of MdtB and MdtC subunits in the heterotrimeric efflux transporter MdtB(2)C complex of Escherichia coli.

PMID 22559837 · 2012

Mutation in mdtB reduces cloxacillin efflux activity.

Mutation Information

Nucleotide Change: G610C
Organisms: Escherichia coli
Confers Resistance To: cloxacillin
Effect on Function: reduces cloxacillin efflux activity
Validation Method: cloxacillin efflux activity measurement
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research