ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeL421P

Validation StatusEstablished

Databases

Card Database

Overview

Mechanism: single resistance variant
Resistance To: beta lactams
Organisms: Neisseria meningitidis
Papers: 1

Paper Information1

Mutations in ponA, the gene encoding penicillin-binding protein 1, and a novel locus, penC, are required for high-level chromosomally mediated penicillin resistance in Neisseria gonorrhoeae.

PMID 11850260 · 2002

Neisseria gonorrhoeae PBP1 conferring resistance to beta-lactam antibiotics; CARD accession: CARD:3004833

Mutation Information

pbp1: p.L421P

Protein Change: L421P
Organisms: Neisseria meningitidis
Confers Resistance To: beta lactams
Effect on Function: single resistance variant
Source Database: Card Database

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