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Browse Mutations phoPR117L

GenephoP

Protein ChangeR117L

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, two-component system response regulator PhoP
Resistance To: colistin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates.

PMID 24412662 · 2014

Pseudomonas mutant PhoP conferring resistance to colistin; CARD accession: CARD:3003895

phoP

Mutation Information

Protein Change: R117L
Organisms: Pseudomonas aeruginosa
Confers Resistance To: colistin
Effect on Function: single resistance variant; two-component system response regulator PhoP
Source Database: Card DatabaseReference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
Help
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research