ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeF25I

Validation StatusConfirmed2+ DBs

Databases

Card DatabaseReference Gene Catalog

Overview

Mechanism: single resistance variant, dihydropteroate synthase FolP
Resistance To: sulfonamides
Organisms: Streptococcus pyogenes
Papers: 1

Paper Information1

Sulfonamide resistance in Streptococcus pyogenes is associated with differences in the amino acid sequence of its chromosomal dihydropteroate synthase.

PMID 9593127 · 1998

Streptococcus pyogenes folP with mutation conferring resistance to sulfonamides; CARD accession: CARD:3003387

folP

Mutation Information

folP: p.F25I

Protein Change: F25I
Organisms: Streptococcus pyogenes
Confers Resistance To: sulfonamides
Effect on Function: single resistance variant; dihydropteroate synthase FolP
Source Database: Card DatabaseReference Gene Catalog

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