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Browse Mutations dacBL145P

GenedacB

Protein ChangeL145P

Validation StatusEstablished

Databases

Reference Gene Catalog

Overview

Mechanism: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB
Resistance To: cephalosporins
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Restoring ceftolozane susceptibility: a role for diazabicyclooctane β-lactamase inhibitors?

PMID 39873500 · 2025

dacB

Mutation Information

Protein Change: L145P
Organisms: Pseudomonas aeruginosa
Confers Resistance To: cephalosporins
Effect on Function: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine endopeptidase DacB
Source Database: Reference Gene Catalog

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research