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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations murAN197D

GenemurA

antibiotic-resistant murA transferase

Protein ChangeN197D

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftriaxone
Papers: 1

Paper Information1

1

MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling.

PMID 35294506 · 2022

Both mutations stabilize MurA and enhance ceftriaxone resistance.

Mutation Information

Protein Change: N197D
Confers Resistance To: ceftriaxone
Validation Method: MIC testing and fluorescence microscopy; growth experiments and ceftriaxone resistance testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research