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Browse Mutations mexCE251Q

GenemexC

MexCD-OprJ efflux pump component

Protein ChangeE251Q

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ciprofloxacin|levofloxacin, levofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Differences in antimicrobial resistance between exoU and exoS isolates of Pseudomonas aeruginosa.

PMID 40261546 · 2025

Mutations in mexC were associated with fluoroquinolone resistance.

Mutations in MexC correlate with levofloxacin resistance

Mutation Information

Protein Change: E251Q
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ciprofloxacin|levofloxacinlevofloxacin
Validation Method: whole genome sequencing and antibiotic susceptibility testing; association with resistance
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research