Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations blaCI105R

GeneblaC

beta-lactamase

Protein ChangeI105R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: clavulanic acid|avibactam
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

A glycine at position 105 leads to clavulanic acid and avibactam resistance in class A β-lactamases.

PMID 40484381 · 2025

Mutations at position 105 in blaC lead to resistance against clavulanic acid and avibactam.

Mutation Information

Protein Change: I105R
Organisms: Escherichia coli
Confers Resistance To: clavulanic acid|avibactam
Validation Method: MIC testing and deep sequencing; kinetic characterization and structural analysis
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research