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Browse Mutations blaPenIC69Y

Protein ChangeC69Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime
Organisms: Escherichia coli, Burkholderia pseudomallei
Papers: 1

Paper Information1

1

Burkholderia pseudomallei PenI β-lactamase and variants are potently inhibited by taniborbactam.

PMID 40938351 · 2025

Mutations C69Y and P167S confer increased resistance to ceftazidime.

Mutation Information

blaPenI: p.C69Y

Protein Change: C69Y
Organisms: Escherichia coli, Burkholderia pseudomallei
Confers Resistance To: ceftazidime
Validation Method: MIC testing in isogenic E. coli strains
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research