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Browse Mutations nuoCF562Y

GenenuoC

NADH:quinone oxidoreductase subunit CD

Protein ChangeF562Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: cefiderocol
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

In vitro antimicrobial activity and resistance mechanisms of cefiderocol against clinical carbapenem-resistant gram-negative bacteria.

PMID 41113641 · 2025

Missense mutation in nuoC was identified in E. coli.

Mutation Information

Protein Change: F562Y
Organisms: Escherichia coli
Confers Resistance To: cefiderocol
Validation Method: whole genome sequencing and MIC determination
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research