Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoC β'-subunit of RNA polymerase	E854K	-	-	Staphylococcus aureus	daptomycin	Reslit	Candidate
rpoC	E933Q	-	DNA-directed RNA polymerase subunit beta RpoC	Staphylococcus aureus	beta lactams	Reference Gene Catalog	Established
rpoC RNA polymerase beta' subunit	F452L	T1354C T1356C	-	Mycobacterium smegmatis, Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoC	F452S	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder Database	Confirmed
rpoC RNA polymerase omega subunit	F632S	-	single resistance variant, DNA-directed RNA polymerase subunit beta RpoC	Staphylococcus aureus	vancomycin\|daptomycindaptomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
rpoC RNA polymerase, beta prime subunit	F86C	T257C	-	-	fluoroquinolones	Reslit	Candidate
rpoC RNA polymerase β′ subunit	G1122D	G3365A	-	Bacillus subtilis	cefuroximerifampicin	Reslit	Candidate
rpoC RNA polymerase gamma subunit	G332R	-	-	Mycobacterium tuberculosis	rifampicinethambutol	ResFinder DatabaseReslit	Confirmed
rpoC	G332S	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoC RNA polymerase subunit β'	G367C	-	-	Escherichia coli	tetracycline	Reslit	Candidate