Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| Q781R | - | DNA-directed RNA polymerase subunit beta RpoC | Clostridioides difficile | fidaxomicin | Reference Gene Catalog | Established | |
rpoC RNA polymerase omega subunit | Q961K | - | single resistance variant, DNA-directed RNA polymerase subunit beta RpoC | Staphylococcus aureus | vancomycin|daptomycindaptomycin | Card DatabaseReference Gene CatalogReslit | Confirmed |
rpoC RNA polymerase omega subunit | R69P | - | - | Mycobacterium bovis | rifampicin | Reslit | Candidate |
| R739S | - | DNA-directed RNA polymerase subunit beta RpoC | Staphylococcus aureus | beta lactams | Reference Gene Catalog | Established | |
| R89G | - | DNA-directed RNA polymerase subunit beta RpoC | Clostridioides difficile | fidaxomicin | Reference Gene Catalog | Established | |
rpoC RNA polymerase beta' subunit | S377A | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoC RNA polymerase beta' subunit | S428T | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoC RNA polymerase beta subunit | S453F | - | - | Staphylococcus capitis | daptomycin | Reslit | Candidate |
| S852Y | - | DNA-directed RNA polymerase subunit beta RpoC | Staphylococcus aureus | beta lactams | Reference Gene Catalog | Established | |
rpoC RNA polymerase, beta prime subunit | S86F | - | - | fluoroquinolones | Reslit | Candidate |
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