Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpsL ribosomal protein S12	K88R	A263G A263C ACA>ATT A264G A265G	Target modification, single resistance variant, 30S ribosomal protein S12	Mycobacterium tuberculosis, Campylobacter jejuni, Mycobacterium bovis, Bifidobacterium adolescentis, Borrelia burgdorferi, Francisella tularensis, Streptomyces albus, Escherichia coli, Campylobacter coli, Campylobacter spp., E. coli, Haemophilus parasuis, Mycobacterium smegmatis, C. jejuni	streptomycinstreptomycin\|amikacin\|gentamicin\|kanamycin\|tobramycin	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpsL	K88T	-	-	Mycobacterium tuberculosis	streptomycin	ResFinder DatabaseReslit	Confirmed
rpsL ribosomal protein S12	K91Q	A272C	-	-	streptomycin	Reslit	Candidate
rpsL streptomycin resistance	L165R	-	-	-	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	L43A	-	-	Mycobacterium tuberculosis	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	L88A	-	-	Mycobacterium tuberculosis	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	P42S	-	-	Streptomyces diastatochromogenes	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	P90R	-	-	Escherichia coli	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	P90S	-	impairs ribosome performance	Salmonella enterica, Escherichia coli, Mycobacterium tuberculosis	streptomycin	Reslit	Candidate
rpsL ribosomal protein S12	P91H	-	-	Deinococcus geothermalis	streptomycin	Reslit	Candidate