Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
murA UDP-N-acetylglucosamine-3-enolpyruvyltransferase	D369N	-	single resistance variant	Escherichia coli	fosfomycin	Card DatabaseReslit	Confirmed
murA UDP-N-acetylglucosamine enolpyruvyl transferase	D390A	-	-	E. coli	fosfomycin	Reslit	Candidate
murA	D396N	-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA	Escherichia coli	fosfomycin	Reference Gene Catalog	Established
murA UDP-N-acetylglucosamine enolpyruvyl transferase	E139K	-	-	E. coli	fosfomycin	Reslit	Candidate
murA UDP-N-acetylmuramate pyrophosphorylase	E271Q	-	-	Staphylococcus aureus	fosfomycin	Reslit	Candidate
murA UDP-N-acetylmuramate pyrophosphorylase	E291D	-	decreased binding affinity of fosfomycin, single resistance variant, UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA	Staphylococcus aureus	fosfomycin	Card DatabaseReference Gene CatalogReslit	Confirmed
murA UDP-N-acetylglucosamine enolpyruvyl transferase	F151S	-	-	E. coli	fosfomycin	Reslit	Candidate
murA UDP-N-acetylmuramate--alanine ligase	G116D	-	-	Actinobacteria, Gammaproteobacteria	penicillin	Reslit	Candidate
murA enzyne	G117W	-	-	Staphylococcus aureus	fosfomycin	Reslit	Candidate
murA UDP-N-acetylmuramate pyrophosphorylase	G240R	-	-	Staphylococcus aureus	fosfomycin	Reslit	Candidate