Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
nfxB transcriptional repressor of MexCD-OprJ efflux pump | L26P | - | - | Pseudomonas aeruginosa | ciprofloxacinazithromycin|ciprofloxacin|cefepime | Reslit | Candidate |
nfxB negative regulator of MexCD-OprJ efflux pump | L29P | - | - | Pseudomonas aeruginosa | azithromycin|ciprofloxacin|cefepime | Reslit | Candidate |
nfxB Regulator of the MexCD-OprJ efflux pump | L456P | - | - | Pseudomonas aeruginosa | ceftazidime avibactam|ceftolozane tazobactam | Reslit | Candidate |
nfxB negative regulator of MexCD-OprJ efflux pump | L83P | - | - | Pseudomonas aeruginosa | azithromycin|ciprofloxacin|cefepime | Reslit | Candidate |
| M115V | - | - | Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa | delafloxacin|gepotidacin|omadacycline | Reslit | Candidate | |
nfxB transcriptional repressor of MexCD-OprJ efflux pump | Q67X | - | - | Pseudomonas aeruginosa | ciprofloxacin | Reslit | Candidate |
nfxB transcriptional repressor of MexCD-OprJ efflux pump | R102G | - | - | Pseudomonas aeruginosa | ciprofloxacin | Reslit | Candidate |
nfxB regulator of MexCD-OprJ efflux pump | R21H | - | - | - | ciprofloxacin | Reslit | Candidate |
| R42G | - | efflux pump transcriptional repressor NfxB | Pseudomonas aeruginosa | quinolones | Reference Gene Catalog | Established | |
| R42H | - | efflux pump transcriptional repressor NfxB | Pseudomonas aeruginosa | colistin | Reference Gene Catalog | Established |
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