Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2 penicillin-binding protein 2	D156N	-	-	Staphylococcus aureus	ceftaroline	Reslit	Candidate
pbp2 penicillin-binding protein 2	D156Y	-	-	Staphylococcus aureus	oxacillin\|cefoxitin\|penicillin	Reslit	Candidate
pbp2 penicillin-binding protein 2	D350A	-	-	Acinetobacter baumannii	carbapenems\|cephalosporins	Reslit	Candidate
pbp2 penicillin-binding protein	D354A	-	-	Klebsiella pneumoniae	ceftazidime avibactam	Reslit	Candidate
pbp2 penicillin-binding protein 2	D365A	-	-	Acinetobacter baumannii	carbapenems\|cephalosporins	Reslit	Candidate
pbp2 penicillin-binding protein 2	E183A	-	-	Staphylococcus aureus	ceftobiprole\|ceftriaxone\|cefazolin\|nafcillin\|ampicillin	Reslit	Candidate
pbp2 penicillin-binding protein 2	E572G	-	single resistance variant	Helicobacter pylori	amoxicillin	Card DatabaseReslit	Confirmed
pbp2 penicillin-binding protein 2	F241R	-	-	Staphylococcus aureus	ceftobiprole\|ceftriaxone\|cefazolin\|nafcillin\|ampicillin	Reslit	Candidate
pbp2 penicillin-binding protein 2	F44S	-	-	Staphylococcus aureus	oxacillin	Reslit	Candidate
pbp2 penicillin-binding protein 2	F504L	-	lower affinity for ceftriaxone and restrict conformational changes that normally accompany acylation, single resistance variant	Neisseria gonorrhoeae, Neisseria meningitidis	penicillinceftazidime\|ceftriaxonebeta lactams	Card DatabaseReslit	Confirmed