Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x penicillin-binding protein 2x	Q405K	-	-	Streptococcus pneumoniae, Streptococcus mitis	penicillin\|cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q453H	-	-	Streptococcus suis	ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein	Q548E	-	confers resistance	Streptococcus gordonii	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q552E	C1654G	-	Streptococcus pneumoniae	penicillin\|cefotaximepenicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	Q554E	-	-	Streptococcus uberis	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q557E	-	substitutions in PBP2X are associated with penicillin non-susceptibility, penicillin-binding protein 2X	Streptococcus agalactiae	penicillin\|cefotaxime\|cefoxitin\|cefazolinpenicillinbeta lactams	Reference Gene CatalogReslit	Confirmed
pbp2x penicillin-binding protein 2X	Q633E	-	-	Streptococcus pneumoniae	amoxicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	R384G	-	decreased the affinity of the protein for a β-lactam, single resistance variant	Streptococcus pneumoniae	penicillinpenicillin\|cefotaximemeropenem+1 more	Card DatabaseReslit	Confirmed
pbp2x penicillin-binding protein 2X	R551C	-	-	Streptococcus suis	penicillin\|ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein 2x	S389L	-	-	Streptococcus pneumoniae, Streptococcus mitis	penicillin\|cefotaxime	Reslit	Candidate