ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemtrR

transcriptional repressor

Protein ChangeA39Y

Nucleotide ChangeG115A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: erythromycin|azithromycin|penicillin
Papers: 1

Paper Information1

Phenotypic and genotypic analyses of Neisseria gonorrhoeae isolates that express frequently recovered PorB PIA variable region types suggest that certain P1a porin sequences confer a selective advantage for urogenital tract infection.

PMID 18541655 · 2008

The G>A substitution at nucleotide 115 in the mtrR structural gene causes an Ala39>Tyr substitution in the MtrR protein.

Mutation Information

mtrR: p.A39Y / c.G115A

Protein Change: A39Y
Nucleotide Change: G115A
Confers Resistance To: erythromycin|azithromycin|penicillin
Validation Method: PCR amplification and sequencing
Source Database: Reslit

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