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Browse Mutations rpoBV408G

GenerpoB

Protein ChangeV408G

Nucleotide ChangeT1225G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifampicin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Novel Chemical Scaffolds for Inhibition of Rifamycin-Resistant RNA Polymerase Discovered from High-Throughput Screening.

PMID 28027449 · 2017

Mutations in the rpoB gene were analyzed for their impact on rifampin resistance.

Mutation Information

rpoB: p.V408G / c.T1225G

Protein Change: V408G
Nucleotide Change: T1225G
Organisms: Escherichia coli
Confers Resistance To: rifampicin
Validation Method: high-throughput screening and subsequent confirmation
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research