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Browse Mutations dacAD171A

GenedacA

diadenylate cyclase

Protein ChangeD171A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: disrupts the catalytic capability of DacA
Resistance To: cefuroxime
Organisms: Listeria monocytogenes
Papers: 1

Paper Information1

1

c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance and osmoregulation.

PMID 28097715 · 2017

Mutation in dacA leads to cefuroxime resistance

Mutation Information

Protein Change: D171A
Organisms: Listeria monocytogenes
Confers Resistance To: cefuroxime
Effect on Function: disrupts the catalytic capability of DacA
Validation Method: disk diffusion
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research