ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneclpC1

ATP-dependent ATPase

Protein ChangeG99D

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: pyrazinamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Mutation in clpC1 encoding an ATP-dependent ATPase involved in protein degradation is associated with pyrazinamide resistance in Mycobacterium tuberculosis.

PMID 28196969 · 2017

Mutation Information

clpC1: p.G99D

Protein Change: G99D
Organisms: Mycobacterium tuberculosis
Confers Resistance To: pyrazinamide
Validation Method: whole-genome sequencing and Sanger DNA sequencing
Source Database: Reslit

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