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Browse Mutations mexRC3T

GenemexR

intergenic region near efflux pump regulator

Nucleotide ChangeC3T

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: interferes with the regular transcription of the efflux component MexA
Resistance To: carbenicillin|cef|ciprofloxacin
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

The Genomic Basis of Rapid Adaptation to Antibiotic Combination Therapy in Pseudomonas aeruginosa.

PMID 32931584 · 2021

Variant in the intergenic region of mexR/A

Mutation Information

Nucleotide Change: C3T
Organisms: Pseudomonas aeruginosa
Confers Resistance To: carbenicillin|cef|ciprofloxacin
Effect on Function: interferes with the regular transcription of the efflux component MexA
Validation Method: experimental validation through dose-response curves and checkerboard assays
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research