Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3-β4 loop to favor a low-affinity drug-binding state.
All mutations are in the β3–β4 loop of PBP2 and contribute to ceftriaxone resistance by altering the conformational dynamics of the protein.
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