ResLit - Antimicrobial Resistance Gene & Mutation Database

Generrl

23S rRNA

Nucleotide ChangeT288C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: clarithromycin
Organisms: M. intracellulare, M. colombiense
Papers: 1

Paper Information1

Diversity and antimicrobial resistance profiles of Mycobacterium avium complex clinical isolates in Thailand based on whole genome comparative analysis.

PMID 39755794 · 2025

Mutations in the 23S rRNA gene (rrl) are associated with clarithromycin resistance in M. intracellulare subsp. chimaera and M. colombiense.

Mutation Information

rrl: c.T288C

Nucleotide Change: T288C
Organisms: M. intracellulare, M. colombiense
Confers Resistance To: clarithromycin
Validation Method: SNP analysis and phenotypic antimicrobial susceptibility testing
Source Database: Reslit

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