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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations ampCE247G

GeneampC

beta-lactamase

Protein ChangeE247G

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftolozane
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Restoring ceftolozane susceptibility: a role for diazabicyclooctane β-lactamase inhibitors?

PMID 39873500 · 2025

Mutations in ampC were the primary mechanism of TOL-TAZ resistance.

Mutation Information

Protein Change: E247G
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftolozane
Validation Method: whole-genome sequencing and MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research