ResLit - Antimicrobial Resistance Gene & Mutation Database

GenepenA

penicillin-binding protein 2 (PBP 2)

Protein ChangeA376P

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: cephalosporins
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

Molecular Detection of Mutations in the penA and 23S rRNA Genes of Neisseria gonorrhoeae Related to Decreased Cephalosporin and Azithromycin Susceptibility in Rectal Specimens from Men Who Have Sex with Men (MSM) in Lima, Peru.

PMID 40864114 · 2025

mutations in penA gene associated with decreased susceptibility to cephalosporins

Mutation Information

penA: p.A376P

Protein Change: A376P
Organisms: Neisseria gonorrhoeae
Confers Resistance To: cephalosporins
Validation Method: Sanger sequencing
Source Database: Reslit

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