Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations nudCN148D

GenenudC

NAD(+) diphosphatase

Protein ChangeN148D

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: loss of enzymatic activity
Resistance To: isoniazid|ethionamide
Organisms: Mycobacterium abscessus
Papers: 1

Paper Information1

1

The MAB_3513c gene plays a key role in intrinsic resistance of Mycobacterium abscessus to isoniazid and ethionamide.

PMID 41313029 · 2026

Mutations in key active sites of NudC lead to reduced resistance to isoniazid and ethionamide.

Mutation Information

Protein Change: N148D
Organisms: Mycobacterium abscessus
Confers Resistance To: isoniazid|ethionamide
Effect on Function: loss of enzymatic activity
Validation Method: drug susceptibility testing
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research