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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations penAQ291R

GenepenA

penicillin-binding protein 2 (PBP 2)

Protein ChangeQ291R

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftriaxone
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

1

Genetic identification of mutations and MLST types associated with decreased susceptibility to ceftriaxone in Neisseria gonorrhoeae.

PMID 41648021 · 2025

Mutations in PenA are associated with ceftriaxone resistance.

Mutation Information

Protein Change: Q291R
Organisms: Neisseria gonorrhoeae
Confers Resistance To: ceftriaxone
Validation Method: statistical analysis of amino acid frequencies
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research