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Browse Mutations mgrB123del

GenemgrB

regulator

Nucleotide Change123del

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: tigecycline
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

In vitro selection of Staphylococcus aureus mutants resistant to tigecycline with intermediate susceptibility to vancomycin.

PMID 26956508 · 2016

Loss of mgrB function leads to increased efflux activity and tigecycline resistance.

Mutation Information

Nucleotide Change: 123del
Organisms: Staphylococcus aureus
Confers Resistance To: tigecycline
Validation Method: phenotypic assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research