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Browse Mutations mdtMD22A

GenemdtM

efflux pump

Protein ChangeD22A

Nucleotide ChangeGAT->GCA

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: phenicols
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Insight into determinants of substrate binding and transport in a multidrug efflux protein.

PMID 26961153 · 2016

Mutations in the mdtM gene were analyzed for their effect on the efflux of TPP+ and chloramphenicol.

Mutation Information

mdtM: p.D22A / c.GAT->GCA

Protein Change: D22A
Nucleotide Change: GAT->GCA
Organisms: Escherichia coli
Confers Resistance To: phenicols
Validation Method: efflux phenotype assay
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research