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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations thyAT51A

GenethyA

folate-dependent thymidylate synthase

Protein ChangeT51A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: trimethoprim sulfamethoxazole
Organisms: Staphylococcus aureus
Papers: 1

Paper Information1

1

Phenotypic Stability of Staphylococcus Aureus Small Colony Variants (SCV) Isolates from Cystic Fibrosis (CF) Patients.

PMID 31159295 · 2019

Mutations in thyA result in thymidine auxotrophy and resistance to trimethoprim-sulfamethoxazole.

Mutation Information

Protein Change: T51A
Organisms: Staphylococcus aureus
Confers Resistance To: trimethoprim sulfamethoxazole
Validation Method: sequencing of the thyA gene
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research