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Browse Mutations eisW36A

Geneeis

aminoglycoside acetyltransferase

Protein ChangeW36A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: modestly increased affinity of Eis to KAN
Resistance To: kanamycin
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Probing the Robustness of Inhibitors of Tuberculosis Aminoglycoside Resistance Enzyme Eis by Mutagenesis.

PMID 31433614 · 2019

Mutations in the substrate binding site of Eis affect the potency of inhibitors.

Mutation Information

Protein Change: W36A
Organisms: Mycobacterium tuberculosis
Confers Resistance To: kanamycin
Effect on Function: modestly increased affinity of Eis to KAN
Validation Method: mutagenesis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research