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Browse Mutations penPN170Q

GenepenP

beta-lactamase

Protein ChangeN170Q

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: impair catalytic activity
Resistance To: penicillin|cephalosporins
Organisms: Bacillus licheniformis
Papers: 1

Paper Information1

1

Thermostable β-Lactamase Mutant with Its Active Site Conjugated with Fluorescein for Efficient β-Lactam Antibiotic Detection.

PMID 31858033 · 2019

Both mutations impair catalytic activity

Mutation Information

Protein Change: N170Q
Organisms: Bacillus licheniformis
Confers Resistance To: penicillin|cephalosporins
Effect on Function: impair catalytic activity
Validation Method: kinetic analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research