ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneblaKPC

carbapenem-hydrolyzing beta-lactamase

Protein ChangeT243M

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime avibactam
Organisms: Enterobacter cloacae, E. coli
Papers: 1

Paper Information1

Impact of anticancer chemotherapy on the extension of beta-lactamase spectrum: an example with KPC-type carbapenemase activity towards ceftazidime-avibactam.

PMID 31953453 · 2020

Mutations in the omega-loop of KPC-type carbapenemase.

Mutation Information

blaKPC: p.T243M

Protein Change: T243M
Organisms: Enterobacter cloacae, E. coli
Confers Resistance To: ceftazidime avibactam
Validation Method: sequencing
Source Database: Reslit

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