Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations pbp1bN214T

penicillin-binding protein

Protein ChangeN214T

Nucleotide ChangeA641C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: beta lactams
Organisms: Streptococcus pneumoniae
Papers: 1

Paper Information1

1

Genome-wide association analyses of invasive pneumococcal isolates identify a missense bacterial mutation associated with meningitis.

PMID 30643125 · 2019

Mutation Information

pbp1b: p.N214T / c.A641C

Protein Change: N214T
Nucleotide Change: A641C
Organisms: Streptococcus pneumoniae
Confers Resistance To: beta lactams
Validation Method: isogenic strain construction and MIC testing
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research