ResLit - Antimicrobial Resistance Gene & Mutation Database

GeneblaGES

beta-lactamase

Protein ChangeG165S

Nucleotide ChangeG493A

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: carbapenems
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Development of a Novel Loop-Mediated Isothermal Amplification Method to Detect Guiana Extended-Spectrum (GES) β-Lactamase Genes in Pseudomonas aeruginosa.

PMID 30778337 · 2019

The G493A mutation in blaGES leads to carbapenem resistance.

Mutation Information

blaGES: p.G165S / c.G493A

Protein Change: G165S
Nucleotide Change: G493A
Organisms: Pseudomonas aeruginosa
Confers Resistance To: carbapenems
Validation Method: Carba-GES-LAMP assay and sequencing
Source Database: Reslit

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