ResLit - Antimicrobial Resistance Gene & Mutation Database

GenethyA

folate-dependent thymidylate synthase

Protein ChangeD20Y

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: para aminosalicylic acid
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

Determination of critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against para-aminosalicylic acid with clinical isolates with thyA, folC and dfrA mutations.

PMID 36335391 · 2022

Mutation not previously reported

Mutation Information

thyA: p.D20Y

Protein Change: D20Y
Organisms: Mycobacterium tuberculosis
Confers Resistance To: para aminosalicylic acid
Validation Method: whole genome sequencing and MIC testing
Source Database: Reslit

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