ResLit - Antimicrobial Resistance Gene & Mutation Database

GenemexW

resistance-nodulation-cell division (RND) antibiotic efflux pump

Protein ChangeE36K

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime|ceftolozane tazobactam|cefepime|ceftazidime avibactam, ceftazidime|ceftazidime avibactam|cefepime|ceftolozane tazobactam
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

Hypermutator strains of Pseudomonas aeruginosa reveal novel pathways of resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors.

PMID 36399436 · 2022

Mutation in the MexVW efflux pump operon, contributing to resistance to cephalosporin/beta-lactamase inhibitor combinations.

Mutation Information

mexW: p.E36K

Protein Change: E36K
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime|ceftolozane tazobactam|cefepime|ceftazidime avibactamceftazidime|ceftazidime avibactam|cefepime|ceftolozane tazobactam
Validation Method: susceptibility testing of engineered mutants; susceptibility testing in engineered mutants
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

Mutation Information

Browse AMR Mutations

Mutation Information