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Browse Mutations emrEE14Q

GeneemrE

small multidrug resistance (SMR) family efflux pump

Protein ChangeE14Q

Nucleotide ChangeG41C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: kanamycin|tetracycline
Organisms: E. coli
Papers: 1

Paper Information1

1

Activating alternative transport modes in a multidrug resistance efflux pump to confer chemical susceptibility.

PMID 36496486 · 2022

E14Q mutation reduces EmrE functionality

Mutation Information

emrE: p.E14Q / c.G41C

Protein Change: E14Q
Nucleotide Change: G41C
Organisms: E. coli
Confers Resistance To: kanamycin|tetracycline
Validation Method: checkerboard assays and IC50 determination
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research