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Browse Mutations rpoBS485L

GenerpoB

Protein ChangeS485L

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: rifampicin
Organisms: Escherichia coli, Salmonella enterica
Papers: 1

Paper Information1

1

Antibiotic perseverance increases the risk of resistance development.

PMID 36595701 · 2023

Mutations in rpoB were identified as the mechanism of rifampicin resistance.

Mutation Information

Protein Change: S485L
Organisms: Escherichia coli, Salmonella enterica
Confers Resistance To: rifampicin
Validation Method: local sequencing of rpoB gene
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research