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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations pmrAE123D

GenepmrA

polymyxin resistance

Protein ChangeE123D

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: predicted to affect the function of proteins encoded by these genes
Resistance To: colistin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Molecular Epidemiology and Colistin Resistant Mechanism of mcr-Positive and mcr-Negative Clinical Isolated Escherichia coli.

PMID 29250039 · 2017

found in high-MIC isolates

Mutation Information

Protein Change: E123D
Organisms: Escherichia coli
Confers Resistance To: colistin
Effect on Function: predicted to affect the function of proteins encoded by these genes
Validation Method: sequencing and functional analysis
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research