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Browse Mutations ampCP180L

GeneampC

beta-lactamase

Protein ChangeP180L

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: increased activity of the enzyme against the ceftazidime substrate
Resistance To: ceftazidime
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex.

PMID 37192202 · 2023

Mutation Information

Protein Change: P180L
Organisms: Pseudomonas aeruginosa
Confers Resistance To: ceftazidime
Effect on Function: increased activity of the enzyme against the ceftazidime substrate
Validation Method: cloning in P. aeruginosa + MIC testing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research