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Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations icr-MoT287A

phosphoethanolamine--lipid A transferase ICR-Mo

Protein ChangeT287A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: impairs enzymatic activity
Resistance To: colistin
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

Defining ICR-Mo, an intrinsic colistin resistance determinant from Moraxella osloensis.

PMID 29758020 · 2018

Mutations in ICR-Mo impair its enzymatic activity and reduce colistin resistance.

Mutation Information

icr-Mo: p.T287A

Protein Change: T287A
Organisms: Escherichia coli
Confers Resistance To: colistin
Effect on Function: impairs enzymatic activity
Validation Method: MALDI-TOF MS analyses
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research