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Browse Mutations mexBV177A

GenemexB

efflux pump component

Protein ChangeV177A

Nucleotide ChangeG531C

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: cefotaxime|levofloxacin|ciprofloxacin|novobiocin|phenicols|trimethoprim
Organisms: Pseudomonas aeruginosa
Papers: 1

Paper Information1

1

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump.

PMID 37493633 · 2023

Mutations in key MexB residues differentially affect substrate recognition

Mutation Information

mexB: p.V177A / c.G531C

Protein Change: V177A
Nucleotide Change: G531C
Organisms: Pseudomonas aeruginosa
Confers Resistance To: cefotaxime|levofloxacin|ciprofloxacin|novobiocin|phenicols|trimethoprim
Validation Method: MIC testing in P. aeruginosa strains
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research