ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeH552Y

Validation StatusSupported

Databases

Reslit

Overview

Paper Information3

Multicenter study for defining the breakpoint for rifampin resistance in Neisseria meningitidis by rpoB sequencing.

Mutations in rpoB are associated with rifampin resistance in N. meningitidis.

Protein Change: H552Y
Organisms: Neisseria meningitidis
Confers Resistance To: rifampicin
Validation Method: transformation of N. meningitidis with rpoB amplicons and MIC testing
Source Database: Reslit

Rifampin-resistant Neisseria meningitidis.

Mutations in rpoB gene confer resistance to rifampin.

Epidemiology and genetic diversity of invasive Neisseria meningitidis strains circulating in Portugal from 2003 to 2020.

Protein Change: H552Y
Organisms: Neisseria meningitidis
Confers Resistance To: rifampicin
Validation Method: whole genome sequencing and antimicrobial susceptibility testing
Source Database: Reslit

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