Browse AMR Mutations

Mutation Information

Protein Change

W46C

Organisms

Klebsiella pneumoniae

Confers Resistance To

nitrofurantoin

Effect on Function

modification or loss of NfsB is a well-known mechanism of nitrofurantoin resistance in E. coli, leading to inactivated or poor catalytic function; oxygen-insensitive NAD(P)H nitroreductase NfsB

Validation Method

genomic analysis

Source Database

ReslitReference Gene Catalog