Home Browse Genes Browse Mutations Download Collaborators About

Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research

Home Browse Genes Browse Mutations Download Collaborators About

Browse Mutations tet(A)V55M

tetracycline resistance

Protein ChangeV55M

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: positive role in conferring tigecycline resistance
Resistance To: tigecycline
Organisms: E. coli
Papers: 1

Paper Information1

1

Tigecycline Sensitivity Reduction in Escherichia coli Due to Widely Distributed tet(A) Variants.

PMID 38138144 · 2023

The V55M mutation was unequivocally validated for its positive role in conferring tigecycline resistance.

Mutation Information

Protein Change: V55M
Organisms: E. coli
Confers Resistance To: tigecycline
Effect on Function: positive role in conferring tigecycline resistance
Validation Method: cloning in E. coli DH5alpha and MIC testing
Source Database: Reslit

Comments (0)

No comments yet. Be the first to comment!

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research