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Browse Mutations blaKPCL169M

carbapenem-hydrolyzing beta-lactamase

Protein ChangeL169M

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime|avibactam
Papers: 1

Paper Information1

1

The Klebsiella pneumoniae carbapenemase (KPC) β-Lactamase Has Evolved in Response to Ceftazidime Avibactam.

PMID 38247599 · 2023

Mutations identified through phylogenetic analysis and correlation with CAZ-AVI resistance.

Mutation Information

blaKPC: p.L169M

Protein Change: L169M
Confers Resistance To: ceftazidime|avibactam
Validation Method: phylogenetic analysis and previous studies
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research