Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
The Klebsiella pneumoniae carbapenemase (KPC) β-Lactamase Has Evolved in Response to Ceftazidime Avibactam.
Mutations identified through phylogenetic analysis and correlation with CAZ-AVI resistance.
Optimal ceftazidime/avibactam dosing exposure against KPC-producing Klebsiella pneumoniae.
The V240G mutation in blaKPC was identified in isolate KP1491, resulting in reduced susceptibility to ceftazidime/avibactam.
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