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Browse Mutations blaKPC261-275ins

carbapenem-hydrolyzing beta-lactamase

Nucleotide Change261-275ins

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: ceftazidime avibactam
Organisms: Enterobacteriaceae, E. coli, Klebsiella pneumoniae
Papers: 1

Paper Information1

1

KPC Beta-Lactamases Are Permissive to Insertions and Deletions Conferring Substrate Spectrum Modifications and Resistance to Ceftazidime-Avibactam.

PMID 33020157 · 2020

mutations in blaKPC confer resistance to ceftazidime-avibactam

Mutation Information

blaKPC: c.261-275ins

Nucleotide Change: 261-275ins
Organisms: Enterobacteriaceae, E. coli, Klebsiella pneumoniae
Confers Resistance To: ceftazidime avibactam
Validation Method: PCR amplification and sequencing
Source Database: Reslit

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ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research